Subcallosal Cingulate

FDG-PET as a pre-operative biomarker for predicting and optimizing response to subcallosal cingulate area deep brain stimulation

Background: Deep brain stimulation targeting the subcallosal cingulate area (SCC-DBS) has emerged as a promising therapy for treatment-resistant depression (TRD). However, only half to two thirds of patients experience meaningful clinical response, …

Lack of neuropsychological effects following short-term subcallosal cingulate gyrus deep brain stimulation in treatment-resistant depression: a randomised crossover study

Background: The subcallosal cingulate gyrus (SCG) is integral to cognitive function and mood regulation. Open-label SCG deep brain stimulation (DBS) studies demonstrate improvement or stabilisation of cognitive function in treatment-resistant …